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Ärzte und akademische Mitarbeiter des Medizinischen Labors Bremen haben eine Vielzahl von Publikationen zu labormedizinisch-analytischen und mikrobiologisch relevanten Themen erstellt oder an deren Erstellung mitgewirkt. Wir haben für Sie eine Auswahl dieser wissenschaftlichen Veröffentlichungen zur Recherche zusammengestellt. Bei Rückfragen stehen Ihnen die Autoren gern zur Verfügung.

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Sputtek A, Humpe A

Kryokonservierung von Blutzellen und hämatopoetischen Stammzellen

In: Transfusionsmedizin und Immunhämatologie, 5. Auflage (Hrsg.: V. Kiefel, U. Sachs), pp. 247-262, Springer, Berlin (2026)

Koeder C, Feuerlein K, Bauer A Zerback T, Weder S, Sputtek A, Längler A, Alexy U, Keller, M

Nutrient status in pregnant vegans and omnivores: An exploratory prospective pilot study (PREGGIE)

Food Humanity 7:101412 (2026)

Zerback T, Koeder C, Weder S, Sputtek A, Eckert, GP, Keller M

Vegan multinutrient supplementation significantly increases Omega-3 index and 25-OH-vitamin D status: a randomized, double-blind, placebo-controlled trial in healthy young vegans

Prostaglandins Leukot Essent Fatty Acids 210:102759 (2026)

Konen F F, Wurster U, Schwenkenbecher P, Gerritzen A, Gross  C C, Eichhorn P, Harrer  A, Isenmann S, Lewczuk P, Lewerenz J, Leypoldt F, Otto M, Regeniter A, Roskos M, Ruprecht K, Spreer A, Strik H, Uhr M, Wick M, Wildemann B, Wiltfang J, Zimmermann T, Hannich M, Khalil M, Tumani H, Süsse M, Skripuletz T
Liquormarker bei Multipler Sklerose. NeuroTransmitter
(10.1007/s15016-025-3987-y) (May 2025)

Konen F F, Wurster U, Schwenkenbecher P, Gerritzen A, Großm C C, Eichhorn P, Harrer A, Isenmann S, Lewczuk P, Lewerenz J, Leypoldt F, Otto M, Regeniter A, Roskos M, Ruprecht K, Spreer A, Strik H, Uhr M, Wick M, Wildemann B, Skripuletz T
Oligoclonal bands and kappa free light chains: Competing parameters or complementary biomarkers? Autoimmunity Reviews
(10.1016/j.autrev.2025.103765) (Feb. 2025) 

Zerback T, Koeder C, Weder S, Sputtek A, Eckert GP, Keller M

Multinutrient supplementation improves selenium and iodine status but has no clear impact on iron and zinc in apparently healthy vegans

JAND Global Reports, 10000 (2025)

Zerback T, Koeder, C, Weder S, Sputtek A, Eckert, GP, Keller M

Assessment of vitamin A, vitamin B2, vitamin B12, vitamin K, folate, and choline status following 4 months of multinutrient supplementation in healthy vegans: a randomised, double-blind, placebo-controlled trial

Eur J Nutr 65, 9 (2025)

Heitland P, Pragst F, Hartwig S, Köster HD 
Thallium distribution along segmented single hairs in a case of a criminal poisoning,
J Anal Toxicol 49 (2025)

Heitland P, A. Raab A, Krell S 
Unexpected arsenic compound in routine determination of arsenic species in urine,
J Trace El Med Biol (2025) (in publication process)

Hart X, Gründer G, Sputtek A, Zurek G

Assessing the validity of revised therapeutic reference ranges for psychotropic drugs: A comparative analysis of updated ranges and real-world distributions in a medical laboratory settig

J Lab Med 48, eA25-eA26 (2024)

Krell S, Heitland P, Hoppe H W, Köster H D 
Klinische Anwendung und diagnostische Fälle der Elementspeziesanalytik,
J Lab Med 48, eA56-57 (2024)

Först C, Ulrich S, Zurek G, Seifert S, Frank M, Scheidel B
Plasma Concentrations of Tranylcypromine in Depressed Patients With Chronic Kidney Disease: Two Case Reports. J Clin Psychopharmacol
(10.1097/JCP.0000000000001866) (April 2024)

Kuhl L, Keller V, Weder S, Alexy U, Fischer M, Keller M, Michalsen A, Längler A, Sputtek A, Gwozdz W

The environmental impacts of omnivorous, vegetarian, and vegan children and adolescents in Germany: Results of the VeChi Diet and VeChi Youth Studies.

Proceedings 91, 423 (2023)

Dietrich J, Keller V, Fischer M, Weder S, Alexy U, Michalsen A, Längler A, Sputtek A, Keller M

Nutrient intake from fortified foods and supplements in vegan, vegetarian, and omnivorous participants aged 6 to 18 years in Germany: Results from the VeChi Youth Study.

Proceedings 91, 429 (2023)

Krell S, Heitland P
Gadolinium determination - observations in routine diagnostics. 12th International Symposiumon Biological Monitoring in Occupational an Enviromental Health Next generation Biomonitoring
Porto, Portugal. Abstract Book page 156 (June 21-23, 2023)

Scherf-Clave, M, Baumann P, Hart X, Schneider H, Schoretsanitis G, Steimer W, Zernig G, Zurek G
Behind the curtain: Therapeutic drug monitoring of psychotropic drugs from a laboratory analytical perspective
The Drug Monit. (10.1097/FTD.0000000000001092) (Mar. 2023)

Hoppe H W, Fest U, Eckert E, Müller J, Göen, T, Hartwig A
MAK Commision. Glyphosate - Determination of glyphosate and AMPA in urine by GC-MS/MS. Biomonitoring Method Translation of the German version from 2023
MAK Collect Occup Health Saf.; 8(2):Doc053.
 https://doi.org/10.34865/bi107183e8_2o (Jun. 2023)

Hart X, Gründer G, Zurek G, Sputtek A
Comparative study of suggested reference values and observed distributions in daily routine of a medical laboratry
Pharmacopsychiatry 55, 316 (2022)

Stascheit F, Hotter B, Hoffmann S, Kohler S, Lehnerer S, Sputtek A, Meisel A

Calprotectin as potential novel biomarker in myastenia gravis

J Transl Autoimmun 4, 100111 (2021)

Alexy U, Fischer M, Weder S, Längler A, Michalsen A, Sputtek A, Keller M

Nutrient intake and status of German children and adolescents consuming vegetarian, vegan or omnivore diets: Results of the VeChi Youth Study

Nutrients 13, 1707-1723 (2021)

Heitland P, Köster H D
Human biomonitoring of 73 elements in blood, serum, erythrocytes and urine
Journal of Trace Elements in Medicine and Biology 64 (2021) 126706 (2021)
Sputtek A, Fuller B
Science First: Cool is beautyful
Transfusion Medicine and Hemotherapy 2019;46:131-132 (2019)
Siebert AK, Obeid R, Weder S, Awwad HM, Sputtek A, Geisel J, Keller M.
Vitamin B-12-fortified toothpaste improves vitamin status in vegans: a 12-wk randomized placebo-controlled study
Am J Clin Nutr. 105:618-625 (2017)
Wolff D, Gerritzen A
Overnight Enrichment is Essential for Reliable Salmonella PCR Testing from Fecal Samples
Clin.Lab.2017;63:603-606 (01-03-2017)
Heitland P, Schaefer J, Köster HD
ICP-MS/MS as a tool to diagnose cobalt and chromium intoxications caused by metal hip arthroplasties.
Winter Conference on Plasma Spectrochemistry, Münster (2015)
Breuer C, Oh J, Nolkemper D, Achilles E G, Fischer L, Eglite I, Guesmer C, Heitland P, Köster H D, Brinkert F, Singer D, Blohm M
Successful detoxification and liver transplantation in a severe poisoning with a chemical wood preservative containing chromium, copper and arsenic.
Transplantation 99, e29-e30 (2015)
Soufi M, Ruppert V, Kurt B, Heitland P, Köster H D
Labordiagnostik zur Lösung seltener und unerkannter Erkrankungen.
Klinikarzt 44, 22-28 (2015)
Heitland P, Köster H D
Determination of chromium in biological materials by ICP-MS in different medical cases – Analytical challenges and clinical significance.
ICP Inf. Newslet. 39, 1791 (2014)
Dahms K, Sharkova Y, Heitland P, Pankuweit S, Schaefer J R
Cobalt intoxication with the help of Dr House.
Lancet 383, 574 (2014)
Heitland P, Köster H D
Analytik, Toxikologie und klinische Fallbeispiele nach Exposition mit Metallen.
Zbl Arbeitsmed 64, 386-388 (2014)
Zurek G, Kirchherr H, von Ahsen N, Kühn-Velten W N
Insights into a TDM laboratory: daily routine or adventure?
Pharmacopsychiatry (2014) 47 - A5_1
Kirchherr H, Shipkova M, Ahsen N
Improved method for therapeutic drug monitoring of 6-thioguanine nucleotides and 6-methylmercaptopurine in whole-blood by LC/MSMS using isotope-labeled internal standards.
Ther Drug Monit 35:313-321. (2013)
Heitland P
Selenium in serum.
The MAK-Collection Part IV: Biomonitoring methods, Vol. 13, DFG, 249-263 (2013)
Heitland P
Arsenic (total) in urine.
The MAK-Collection Part IV: Biomonitoring methods, Vol. 13, DFG, 25-36 (2013)
Schäd SG, Heitland P, Kühn-Velten W N, Gross G E, Jonas L
Time-dependent decrement of dermal gadolinium deposits and significant improvement of skin symptoms in a patient with nephrogenic systemic fibrosis after temporary renal failure.
J. Cutan. Pathol. 40 (2013), 935-944
Goebel A, Boehm M, Kirchherr H, Kühn-Velten W N
Simultaneous identification and quantification of synthetic cannabinoids (cannabimimetics) in serum, hair, and urine by rapid and sensitive HPLC tandem mass spectrometry screenings: overview and experience from routine testing.
J. Lab. Med. 37 (2013), 167-180
Clajus C, Kühn-Velten W N, Schmidt J J, Lorenzen J M, Pietsch D, Beutel G, Kielstein J T
Cotrimoxazole plasma levels, dialyzer clearance and total removal by extended dialysis in a patient with acute kidney injury: risk of under-dosing using current dosing recommendations.
BMC Pharmacology and Toxicology 14 (2013), 19 (5 pp.)
Bertram A, Haenel S S, Hadem J, Hoeper M M, Gottlieb J, Warnecke G, Kaschinski S, Hafer C, Kühn-Velten W N, Günther D, Kielstein J T
Tissue concentration of paraquat on day 32 after intoxication and failed bridge to transplantation by extracorporeal membrane oxygenation therapy.
BMC Pharmacology and Toxicology 14 (2013), 45 (6 pp.)
Roehl A B, Zoremba N, Kipp M, Schiefer J, Goetzenich A, Bleilevens C, Kühn-Velten W N, Tolba R, Rossaint R, Hein M
The effects of levosimendan on brain metabolism during initial recovery from global transient ischaemia/hypoxia.
BMC Neurology 12 (2012), 81 (10 pp.)
Heitland P, Köster H D
Applications of ICP-MS in human biomonitoring studies.
S. Caroli and G. Zaray, eds., Analytical Techniques for Clinical Chemistry, Wiley VCH, 367-395 (2012)
Gerritzen A, Wittke J W, von Ahsen N, Wolff D
Direct faecal PCR for diagnosis of Shiga-toxin-producing Escherichia coli.
Lancet Infect Dis 02/2012;12(2):102. DOI:10.1016/S1473-3099(11)70369
Gerritzen A, Brandt S
Serodiagnosis of Lyme borreliosis with bead based immunoassys using multiplex technology.
Methods 03/2012;56(4):477-83. DOI:10.1016/j.ymeth.2012.02.007
Wolff D, Gerritzen A
Evaluation of a Real-Time PCR Assay for the detection, genotyping and quantification of Borrelia burgdorferi sensu lato in Ixodes ticks in a routine laboratory setting.
Clin Lab 01/2011; 57(1-2):67-73
Wolff D, Gerritzen A
Sensitive and quantitative Cytomegalovirus PCR: Comparison of the LightMix hCMV and the Real Art CMV LC PCR Kits.
Clin Biochem 05/2011; 44(7):548.DOI:10.1016/j.clinbiochem.2011.03.122
Gerritzen A, Wittke J W, Wolff D
Rapid and sensitive detection of shiga toxin-producing Escherichia coli directly from stool samples by real-time PCR in comparison to culture, enzyme immunoassay and vero cell cytotoxicity assay.
Clin Lab 01/2011;57(11-12)993-8
Eden G, Busch M, Kühn-Velten W N, Schneider A, Kielstein J T
Successful treatment of life-threatening pentoxifylline intoxication by high-flux hemodialysis.
Clin. Nephrol. 75 (2011,) 171-173
Hiemke C, Baumann P, Bergemann N, Conca A, Dietmaier O, Egberts K, Fric M, Gerlach M, Greiner C, Gründer G, Haen E, Havemann-Reinecke U, Jaquenoud Sirot E, Kirchherr H, Laux G, Lutz U C, Messer T, Müller M J, Pfuhlmann B, Rambeck B, Riederer P, Schoppek B, Stingl J, Uhr M, Ulrich S, Waschgler R, Zernig G
AGNP consensus guidelines for therapeutic drug monitoring in psychiatry: update 2011
Pharmacopsychiatry (2011) 44(6):195-235
Kröger N, Asenova S, Gerritzen A, Bacher U, Zander A
Questionable role of free light chain assay ratio to determine stringent complete remission (sCR) multiple myeloma patients.
Blood, Comment (January 2010); 115 (16): 3413-3414
Wolff D, Gerritzen A
Evaluation of a Real-Time PCR Assay for the detection, genotyping and quantification of Borrelia burgdorferi sensu lato in Ixodes ticks in a routine laboratory setting.
Clin Chem Lab Med 01/2010; 57(1-2):67-73.
Gerritzen A, Brandt S
Evaluation of a novel EIA detectingsecretory IgA in Feces.
Clin Chem Lab Med 01/2010;49:A140
Gerritzen A, Brandt S
Newly calibrated ß-amyloid ratio in CSF for improved Alzheimer detection.
Clin Chem Lab Med 01/2010;49:A140
Heitland P, Köster H D
Concentration Ranges Of Trace Elements In Human Blood, Plasma, Erythrocytes and Urine.
ICP Inf. Newslet. 35, 1223 (2010)
Roehl A, Kühn-Velten W N, Goetzenich A, Hein M
Diffuse myocardial damage by levosimendan used for postconditioning in myocardial ischemia reperfusion injury.
Crit. Care Med. 38 No. 12 Suppl. (2010), 125
Hoppe H W
PFOA in Plasma.
J.Angerer and K.-H.Schaller (eds.): The MAK-Collection for OccupationaL Health and Safety, Part IV: Biomonitoring Methods, Volume 12, Wiley-VCH, Weinheim (2010)
Hoppe H W
Butyl tin compounds (mono-,di-, tri- and tetrabutyltin).
J.Angerer (eds.): The MAK-Collection for OccupationaL Health and Safety, Part IV: Biomonitoring Methods, Volume 12, Wiley-VCH, Weinheim (2010)
Hoppe H W
Di (2-ethylhexyl)phthalate (DEHP) metabolites.
J.Angerer (eds.): The MAK-Collection for OccupationaL Health and Safety, Part IV: Biomonitoring Methods, Volume 12, Wiley-VCH, Weinheim (2010)
Gerritzen A, Wolff D
Zeckenschnelltest auf Borrelien jetzt noch genauer.
BorrelioseWissen Nr. 19, 2/2009, herausgegeben vom Borreliose und FSME Bund Deutschland
Gerritzen A
Der Zeckenschnelltest.
U. Fischer und B. Siegmund (Hrsg.): Borreliose-Jahrbuch 2009, p 65 – 70
Wolff D, Brüning T, Gerritzen A
Rapid detection of the Clostridium difficile ribotype 027 tcdC gene frame shift mutation at position 117 by real-time PCR and melt curve analysis.
Eur J Clin Microbiol 04/2009; 28(8):959-62.DOI:10.1007/s10096-009-0731-7
Heitland P, Köster H D
Comparison of different medical cases in urinary arsenic speciation by fast HPLC-ICP-MS.
Int. J. Hyg. Environ. Health 212, 432-438 (2009)
Kirchherr H
Data Evaluation in LC-MS.
Kromidas S, Kuss HJ (Ed) Quantification in LC and GC Wiley-VCH 2009
Das A M, Illsinger S, Hartmann H, Oehler K, Bohnhorst B, Kühn-Velten W N, Lücke T
Prenatal benzoate treatment in urea cycle defects.
Arch. Dis. Child. Fetal Neonatal Ed. 94 (2009), F216-F217
Kirchherr H
Auswertung in der LC-MS-Kopplung.
Kromidas S, Kuss HJ (Ed.) Chromatogramme richtig integrieren und bewerten (2008)
Gerritzen A, Wolff D
Bedeutung des HLA-DRB *05, *01-Genotyps als Risikofaktor für eine therapieresistente Lyme-Arthritis.
BorrelioseWissen Nr. 17 (2/2008), herausgegeben von Borreliose und FSME Bund Deutschland
Gerritzen A
Verbesserte Borrelien-Serologie durch Einsatz von rekombinanten Antigenen mit der Luminex-Technologie.
BorrelioseWissen Nr. 17, 2/2008, 14 - 16, herausgegeben vom Borreliose und FSME Bund Deutschland
Schmidt P, Hörmansdörfer C, Pruggmayer M, Schütte C, Neumann A, Gerritzen A et al.
Improved Prenatal Aneuploidy Screening using the Novel Advanced First-Trimester Screening Algorithm: A Multicenter Study of 10,017 Pregnancies.
J Clinical Ultrasound (p 1 – 6, 8/2008)
Heitland P, Köster H D
Fast determination of arsenic species and total arsenic in urine by HPLC-ICP-MS: Concentration ranges for unexposed German inhabitants and clinical case studies.
J. Anal. Toxicol. 32, 308-314 (2008)
Silberschmidt A L, Kühn-Velten W N, Juon A M, Zimmermann R, von Mandach U
Nifedipine concentration in maternal and umbilical cord blood after nifedipine gastrointestinal therapeutic system for tocolysis.
Brit. J. Obstet. Gynaecol. 115 (2008), 480-485
Juon A M, Kühn-Velten W N, Burkhardt T, Krähenmann F, Zimmermann R, von Mandach U
Nifedipine gastrointestinal therapeutic system (GITS) as an alternative to slow-release for tocolysis: Tolerance and pharmacokinetic profile.
Eur. J. Obstet. Gynecol. Reprod. Biol. 140 (2008), 27-32
Schmidt C M, Lewelling H, Bertsch T, Kühn-Velten W N, Schwarz S
Nutritional status in patients with acute exacerbation of multiple sclerosis: a controlled study.
Mult. Scler. 14 (2008), S199
Kühn-Velten W N, Goebel A
A novel HPLC-tandem MS/MS method for quantification of galactitol in urine: diagnosis and monitoring of patients with enzyme deficiencies in galactose metabolism.
Clin. Chem. Lab. Med. 46 (2008), A173
Goebel A, Ahlers-Frömling M, Dietrich M, Stübecke W, Kühn-Velten W N
Use of HPLC-tandem MS/MS and GC/MS to prove high tramadol accumulation in hair of a puerpera.
Clin. Chem. Lab. Med. 46 (2008), A176
Gerritzen  A(Mitarbeit)
Liquordiagnostik
H.-F. Petereit, E. Sindern, M. Wick (Hrsg.) Leitlinien und Methodenkatalog der Deutschen Gesellschaft für Liquordiagnostik und Klinische Neurochemie Springer Medizin Verlag Heidelberg (2007)
Hartung K, ... Gerritzen A et al.
Labordiagnostik rheumatischer Erkrankungen: Infektbedingte Arthritiden.
Z Rheumatol 66: 395-415 (2007)
Wolff D, Gerritzen A
Comparison of the Roche COBAS AMPLICOR™ Monitor, Roche COBAS AMPLIPREP™/COBAS TAQMAN™ and the ABBOTT REALTime™ Test for the Quantification of HCV and HIV-1 RNA.
Clin Chem Lab Med 2007, 45(7):917-922.DOI:10.1515/cclm.2007.149
Schmitt B, Wolters M, Kressel G, Hülsmann O, Ströhle A, Kühn-Velten W N, Lichtinghagen R, Bub A, Barth S W, Stichtenoth D O, Hahn A
Effects of a combined supplementation with B vitamins and antioxidants on plasma levels of asymmetric dimethylarginine (ADMA) in subjects with elevated risk of cardiovascular disease.
Atherosclerosis 193 (2007), 168-176
Lewczuk P, Beck G, Ganslandt O, Esselmann H, Deisenhammer F, Regeniter A, Petereit H F, Tumani H, Gerritzen A et al.
International quality control survey of neurochemical dementia diagnostics.
Neurosci. Lett. 12/2006;409(1):1-4. DOI:10.1016/j.neulet.2006.07.009
Heitland P, Köster H D
Biomonitoring of 30 trace elements in urine of children and adults by ICP-MS.
Clin. Chim. Acta 365, 310-318 (2006)
Heitland P, Köster H D
Biomonitoring of 37 trace elements in blood from inhabitants of northern Germany by ICP-MS.
J. Trace Elem. Med. Biol. 20, 253-262 (2006)
Heitland P, Köster H D
Biomonitoring of 37 trace elements in human blood and plasma from inhabitants of northern Germany by ICP-MS.
International Conference on Environmental Epidemiology and Exposure, Paris (2006)
Heitland P, Köster H D
Biomonitoring von Schwermetallen und essentiellen Spurenelementen.
GZM Netzwerk-Journal, 11 (1), 11-13 (2006)
Kirchherr H, Kühn-Velten W N
Quantitative determination of forty-eight antidepressants and antipsychotics in human serum by HPLC tandem mass spectrometry: A multi-level, single-sample approach.
J. Chromatogr. B 843 (2006), 100-113
Hammer U, Wegener R, Nizze H, Wöhlke G, Kruse C, Dworniczak B, Kühn-Velten W N, Nöldge-Schomburg G, Hofmockel R, Jonas L
Sickle cell anaemia: Conclusions from a forensic case report of a young african woman who died after anaesthesia.
Ultrastruct. Pathol. 30 (2006), 415-422
Kühn-Velten W N, Dräger H, Schröder-Friedrich M, Kirchherr H
Verification of the performance of enzymatic tests for bile acid quantification in faeces by HPLC-tandem MS/MS.
Clin. Chem. Lab. Med. 44 (2006), A163
Hoppe H W
Methylmercury in blood.
J.Angerer and K.-H.Schaller (eds.): DFG-Analyses of Hazardous Substances in Biological Materials, Volume 10. Wiley-VCH, Weinheim (2006)
Gerritzen A, Holzhüter H, Wolff D
Lymphocyte Transformation Test (LTT) as a helpful diagnostic tool to detect active Lyme Borreliosis.
J Med Microbiol 2004; 294S1:136