Publikationen
Ärzte und akademische Mitarbeiter des Medizinischen Labors Bremen haben eine Vielzahl von Publikationen zu labormedizinisch-analytischen und mikrobiologisch relevanten Themen erstellt oder an deren Erstellung mitgewirkt. Wir haben für Sie eine Auswahl dieser wissenschaftlichen Veröffentlichungen zur Recherche zusammengestellt. Bei Rückfragen stehen Ihnen die Autoren gern zur Verfügung.
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Scherf-Clavel, M., Baumann, P., Hart, X., Schneider, H., Schoretsanitis, G., Steimer, W., Zernig, G., Zurek, G.,
Behind the curtain: Therapeutic drug monitoring of psychotropic drugs from a laboratory analytical perspective
The Drug Monit. (10.1097/FTD.0000000000001092) (Mar. 2023) -
Krell, S., Heitland, P.
Gadolinium determination - observations in routine diagnostics. 12th International Symposiumon Biological Monitoring in Occupational an Enviromental Health Next generation Biomonitoring
Porto, Portugal. Abstract Book page 156 (June 21-23, 2023) -
Hoppe, H.-W., Fest, U., Eckert, E., Müller, J., Göen, T., Hartwig, A.,
MAK Commision. Glyphosate - Determination of glyphosate and AMPA in urine by GC-MS/MS. Biomonitoring Method Translation of the German version from 2023
MAK Collect Occup Health Saf.; 8(2):Doc053. https://doi.org/10.34865/bi107183e8_2o (Jun. 2023) -
Hart, X., Gründer, G., Zurek, G., Sputtek, A.,
Comparative study of suggested reference values and observed distributions in daily routine of a medical laboratry
Pharmacopsychiatry 55, 316 (2022) -
P. Heitland und H.D. Köster
Human biomonitoring of 73 elements in blood, serum, erythrocytes and urine
Journal of Trace Elements in Medicine and Biology 64 (2021) 126706 (2021) -
A. Sputtek, B. Fuller
Science First: Cool is beautyful
Transfusion Medicine and Hemotherapy 2019;46:131-132 (2019) -
Siebert AK, Obeid R, Weder S, Awwad HM, Sputtek A, Geisel J, Keller M.
Vitamin B-12-fortified toothpaste improves vitamin status in vegans: a 12-wk randomized placebo-controlled study
Am J Clin Nutr. 105:618-625 (2017) -
Kirchherr H, Shipkova M und von Ahsen N
Improved method for therapeutic drug monitoring of 6-thioguanine nucleotides and 6-methylmercaptopurine in whole-blood by LC/MSMS using isotope-labeled internal standards.
Ther Drug Monit 35:313-321. (2013) -
H. Kirchherr
Auswertung in der LC-MS-Kopplung.
Kromidas S, Kuss HJ (Ed.) Chromatogramme richtig integrieren und bewerten (2008) -
A. Gerritzen (Mitarbeit)
Liquordiagnostik
H.-F. Petereit, E. Sindern, M. Wick (Hrsg.) Leitlinien und Methodenkatalog der Deutschen Gesellschaft für Liquordiagnostik und Klinische Neurochemie Springer Medizin Verlag Heidelberg (2007) -
D. Wolff, A. Gerritzen
Overnight Enrichment is Essential for Reliable Salmonella PCR Testing from Fecal Samples
Clin.Lab.2017;63:603-606 (01-03-2017) -
C. Breuer, J. Oh, D. Nolkemper, E. G. Achilles, L. Fischer, I. Eglite, C. Guesmer, P Heitland, H. D. Köster, F. Brinkert, D. Singer and M. Blohm
Successful detoxification and liver transplantation in a severe poisoning with a chemical wood preservative containing chromium, copper and arsenic.
Transplantation 99, e29-e30 (2015) -
A. Gerritzen, H. Holzhüter, D. Wolff
Lymphocyte Transformation Test (LTT) as a helpful diagnostic tool to detect active Lyme Borreliosis.
J Med Microbiol 2004; 294S1:136 -
A. Gerritzen und D. Wolff
Bedeutung des HLA-DRB *05, *01-Genotyps als Risikofaktor für eine therapieresistente Lyme-Arthritis.
BorrelioseWissen Nr. 17 (2/2008), herausgegeben von Borreliose und FSME Bund Deutschland -
K. Hartung, ... A. Gerritzen et al.
Labordiagnostik rheumatischer Erkrankungen: Infektbedingte Arthritiden.
Z Rheumatol 66: 395-415 (2007) -
A. Gerritzen
Verbesserte Borrelien-Serologie durch Einsatz von rekombinanten Antigenen mit der Luminex-Technologie.
BorrelioseWissen Nr. 17, 2/2008, 14 - 16, herausgegeben vom Borreliose und FSME Bund Deutschland -
P. Schmidt, C. Hörmansdörfer, M. Pruggmayer, C. Schütte, A. Neumann, A. Gerritzen et al.
Improved Prenatal Aneuploidy Screening using the Novel Advanced First-Trimester Screening Algorithm: A Multicenter Study of 10,017 Pregnancies.
J Clinical Ultrasound (p 1 – 6, 8/2008) -
P. Lewczuk, G. Beck, O.Ganslandt, H.Esselmann, F. Deisenhammer, A. Regeniter, H.-F. Petereit, H. Tumani, A. Gerritzen et al.
International quality control survey of neurochemical dementia diagnostics.
Neurosci. Lett. 12/2006;409(1):1-4. DOI:10.1016/j.neulet.2006.07.009 -
P. Heitland and H.D. Köster
Biomonitoring of 30 trace elements in urine of children and adults by ICP-MS.
Clin. Chim. Acta 365, 310-318 (2006) -
P. Heitland und H.D. Köster
Biomonitoring of 37 trace elements in blood from inhabitants of northern Germany by ICP-MS.
J. Trace Elem. Med. Biol. 20, 253-262 (2006) -
P. Heitland und H.D. Köster
Biomonitoring of 37 trace elements in human blood and plasma from inhabitants of northern Germany by ICP-MS.
International Conference on Environmental Epidemiology and Exposure, Paris (2006) -
P. Heitland und H.D. Köster
Biomonitoring von Schwermetallen und essentiellen Spurenelementen.
GZM Netzwerk-Journal, 11 (1), 11-13 (2006) -
Kirchherr H, Kühn-Velten WN
Quantitative determination of forty-eight antidepressants and antipsychotics in human serum by HPLC tandem mass spectrometry: A multi-level, single-sample approach.
J. Chromatogr. B 843 (2006), 100-113 -
Hammer U, Wegener R, Nizze H, Wöhlke G, Kruse C, Dworniczak B, Kühn-Velten WN, Nöldge-Schomburg G, Hofmockel R, Jonas L
Sickle cell anaemia: Conclusions from a forensic case report of a young african woman who died after anaesthesia.
Ultrastruct. Pathol. 30 (2006), 415-422 -
Kühn-Velten WN, Dräger H, Schröder-Friedrich M, Kirchherr H
Verification of the performance of enzymatic tests for bile acid quantification in faeces by HPLC-tandem MS/MS.
Clin. Chem. Lab. Med. 44 (2006), A163 -
H.W.Hoppe
Methylmercury in blood.
J.Angerer and K.-H.Schaller (eds.): DFG-Analyses of Hazardous Substances in Biological Materials, Volume 10. Wiley-VCH, Weinheim (2006) -
D. Wolff and A. Gerritzen
Comparison of the Roche COBAS AMPLICOR™ Monitor, Roche COBAS AMPLIPREP™/COBAS TAQMAN™ and the ABBOTT REALTime™ Test for the Quantification of HCV and HIV-1 RNA.
Clin Chem Lab Med 2007, 45(7):917-922.DOI:10.1515/cclm.2007.149 -
Schmitt B, Wolters M, Kressel G, Hülsmann O, Ströhle A, Kühn-Velten WN, Lichtinghagen R, Bub A, Barth SW, Stichtenoth DO, Hahn A
Effects of a combined supplementation with B vitamins and antioxidants on plasma levels of asymmetric dimethylarginine (ADMA) in subjects with elevated risk of cardiovascular disease.
Atherosclerosis 193 (2007), 168-176 -
P. Heitland and H. D. Köster
Fast determination of arsenic species and total arsenic in urine by HPLC-ICP-MS: Concentration ranges for unexposed German inhabitants and clinical case studies.
J. Anal. Toxicol. 32, 308-314 (2008) -
Silberschmidt AL, Kühn-Velten WN, Juon AM, Zimmermann R, von Mandach U
Nifedipine concentration in maternal and umbilical cord blood after nifedipine gastrointestinal therapeutic system for tocolysis.
Brit. J. Obstet. Gynaecol. 115 (2008), 480-485 -
Juon AM, Kühn-Velten WN, Burkhardt T, Krähenmann F, Zimmermann R, von Mandach U
Nifedipine gastrointestinal therapeutic system (GITS) as an alternative to slow-release for tocolysis: Tolerance and pharmacokinetic profile.
Eur. J. Obstet. Gynecol. Reprod. Biol. 140 (2008), 27-32 -
Schmidt CM, Lewelling H, Bertsch T, Kühn-Velten WN, Schwarz S
Nutritional status in patients with acute exacerbation of multiple sclerosis: a controlled study.
Mult. Scler. 14 (2008), S199 -
Kühn-Velten WN, Goebel A
A novel HPLC-tandem MS/MS method for quantification of galactitol in urine: diagnosis and monitoring of patients with enzyme deficiencies in galactose metabolism.
Clin. Chem. Lab. Med. 46 (2008), A173 -
Goebel A, Ahlers-Frömling M, Dietrich M, Stübecke W, Kühn-Velten WN
Use of HPLC-tandem MS/MS and GC/MS to prove high tramadol accumulation in hair of a puerpera.
Clin. Chem. Lab. Med. 46 (2008), A176 -
A. Gerritzen und D. Wolff
Zeckenschnelltest auf Borrelien jetzt noch genauer.
BorrelioseWissen Nr. 19, 2/2009, herausgegeben vom Borreliose und FSME Bund Deutschland -
A. Gerritzen
Der Zeckenschnelltest.
U. Fischer und B. Siegmund (Hrsg.): Borreliose-Jahrbuch 2009, p 65 – 70 -
D. Wolff, T. Brüning, A. Gerritzen
Rapid detection of the Clostridium difficile ribotype 027 tcdC gene frame shift mutation at position 117 by real-time PCR and melt curve analysis.
Eur J Clin Microbiol 04/2009; 28(8):959-62.DOI:10.1007/s10096-009-0731-7 -
P. Heitland and H. D. Köster
Comparison of different medical cases in urinary arsenic speciation by fast HPLC-ICP-MS.
Int. J. Hyg. Environ. Health 212, 432-438 (2009) -
H. Kirchherr
Data Evaluation in LC-MS.
Kromidas S, Kuss HJ (Ed) Quantification in LC and GC Wiley-VCH 2009 -
Das AM, Illsinger S, Hartmann H, Oehler K, Bohnhorst B, Kühn-Velten WN, Lücke T
Prenatal benzoate treatment in urea cycle defects.
Arch. Dis. Child. Fetal Neonatal Ed. 94 (2009), F216-F217 -
N. Kröger, S. Asenova, A. Gerritzen, U. Bacher, A. Zander
Questionable role of free light chain assay ratio to determine stringent complete remission (sCR) multiple myeloma patients.
Blood, Comment (January 2010); 115 (16): 3413-3414 -
D. Wolff, A. Gerritzen
Evaluation of a Real-Time PCR Assay for the detection, genotyping and quantification of Borrelia burgdorferi sensu lato in Ixodes ticks in a routine laboratory setting.
Clin Chem Lab Med 01/2010; 57(1-2):67-73. -
A. Gerritzen, S. Brandt
Evaluation of a novel EIA detectingsecretory IgA in Feces.
Clin Chem Lab Med 01/2010;49:A140 -
A. Gerritzen, S. Brandt
Newly calibrated ß-amyloid ratio in CSF for improved Alzheimer detection.
Clin Chem Lab Med 01/2010;49:A140 -
P. Heitland and H. D. Köster
Concentration Ranges Of Trace Elements In Human Blood, Plasma, Erythrocytes and Urine.
ICP Inf. Newslet. 35, 1223 (2010) -
Roehl A, Kühn-Velten WN, Goetzenich A, Hein M
Diffuse myocardial damage by levosimendan used for postconditioning in myocardial ischemia reperfusion injury.
Crit. Care Med. 38 No. 12 Suppl. (2010), 125 -
H.W.Hoppe
PFOA in Plasma.
J.Angerer and K.-H.Schaller (eds.): The MAK-Collection for OccupationaL Health and Safety, Part IV: Biomonitoring Methods, Volume 12, Wiley-VCH, Weinheim (2010) -
H.W. Hoppe
Butyl tin compounds (mono-,di-, tri- and tetrabutyltin).
J.Angerer (eds.): The MAK-Collection for OccupationaL Health and Safety, Part IV: Biomonitoring Methods, Volume 12, Wiley-VCH, Weinheim (2010) -
H.W. Hoppe
Di (2-ethylhexyl)phthalate (DEHP) metabolites.
J.Angerer (eds.): The MAK-Collection for OccupationaL Health and Safety, Part IV: Biomonitoring Methods, Volume 12, Wiley-VCH, Weinheim (2010) -
D. Wolff, A. Gerritzen
Evaluation of a Real-Time PCR Assay for the detection, genotyping and quantification of Borrelia burgdorferi sensu lato in Ixodes ticks in a routine laboratory setting.
Clin Lab 01/2011; 57(1-2):67-73 -
D. Wolff and A. Gerritzen
Sensitive and quantitative Cytomegalovirus PCR: Comparison of the LightMix hCMV and the Real Art CMV LC PCR Kits.
Clin Biochem 05/2011; 44(7):548.DOI:10.1016/j.clinbiochem.2011.03.122 -
A. Gerritzen, J.-W. Wittke, D. Wolff
Rapid and sensitive detection of shiga toxin-producing Escherichia coli directly from stool samples by real-time PCR in comparison to culture, enzyme immunoassay and vero cell cytotoxicity assay.
Clin Lab 01/2011;57(11-12)993-8 -
Eden G, Busch M, Kühn-Velten WN, Schneider A, Kielstein JT
Successful treatment of life-threatening pentoxifylline intoxication by high-flux hemodialysis.
Clin. Nephrol. 75 (2011,) 171-173 -
Eden G, Busch M, Kühn-Velten WN, Schneider A, Kielstein JT,
Successful treatment of life-threatening pentoxifylline intoxication by high-flux hemodialysis.
Clin. Nephrol. 75 (2011,) 171-173 -
A. Gerritzen, S. Brandt
Serodiagnosis of Lyme borreliosis with bead based immunoassys using multiplex technology.
Methods 03/2012;56(4):477-83. DOI:10.1016/j.ymeth.2012.02.007 -
A Gerritzen, J-W Wittke, N von Ahsen, D Wolff
Direct faecal PCR for diagnosis of Shiga-toxin-producing Escherichia coli.
Lancet Infect Dis 02/2012;12(2):102. DOI:10.1016/S1473-3099(11)70369 -
P. Heitland and H. D. Köster
Applications of ICP-MS in human biomonitoring studies.
S. Caroli and G. Zaray, eds., Analytical Techniques for Clinical Chemistry, Wiley VCH, 367-395 (2012) -
Roehl AB, Zoremba N, Kipp M, Schiefer J, Goetzenich A, Bleilevens C, Kühn-Velten WN, Tolba R, Rossaint R, Hein M
The effects of levosimendan on brain metabolism during initial recovery from global transient ischaemia/hypoxia.
BMC Neurology 12 (2012), 81 (10 pp.) -
P. Heitland
Selenium in serum.
The MAK-Collection Part IV: Biomonitoring methods, Vol. 13, DFG, 249-263 (2013) -
P. Heitland
Arsenic (total) in urine.
The MAK-Collection Part IV: Biomonitoring methods, Vol. 13, DFG, 25-36 (2013) -
Schäd SG, Heitland P, Kühn-Velten WN, Gross GE, Jonas L
Time-dependent decrement of dermal gadolinium deposits and significant improvement of skin symptoms in a patient with nephrogenic systemic fibrosis after temporary renal failure.
J. Cutan. Pathol. 40 (2013), 935-944 -
Goebel A, Boehm M, Kirchherr H, Kühn-Velten WN
Simultaneous identification and quantification of synthetic cannabinoids (cannabimimetics) in serum, hair, and urine by rapid and sensitive HPLC tandem mass spectrometry screenings: overview and experience from routine testing.
J. Lab. Med. 37 (2013), 167-180 -
Clajus C, Kühn-Velten WN, Schmidt JJ, Lorenzen JM, Pietsch D, Beutel G, Kielstein JT
Cotrimoxazole plasma levels, dialyzer clearance and total removal by extended dialysis in a patient with acute kidney injury: risk of under-dosing using current dosing recommendations.
BMC Pharmacology and Toxicology 14 (2013), 19 (5 pp.) -
Bertram A, Haenel SS, Hadem J, Hoeper MM, Gottlieb J, Warnecke G, Kaschinski S, Hafer C, Kühn-Velten WN, Günther D, Kielstein JT
Tissue concentration of paraquat on day 32 after intoxication and failed bridge to transplantation by extracorporeal membrane oxygenation therapy.
BMC Pharmacology and Toxicology 14 (2013), 45 (6 pp.) -
K. Dahms, Y. Sharkova, P. Heitland, S. Pankuweit and J. R. Schaefer
Cobalt intoxication with the help of Dr House.
Lancet 383, 574 (2014) -
P. Heitland und H. D. Köster
Analytik, Toxikologie und klinische Fallbeispiele nach Exposition mit Metallen.
Zbl Arbeitsmed 64, 386-388 (2014) -
P. Heitland and H. D. Köster
Determination of chromium in biological materials by ICP-MS in different medical cases – Analytical challenges and clinical significance.
ICP Inf. Newslet. 39, 1791 (2014) -
M. Soufi, V. Ruppert, B. Kurt, P. Heitland and H. D. Köster
Labordiagnostik zur Lösung seltener und unerkannter Erkrankungen.
Klinikarzt 44, 22-28 (2015) -
P. Heitland, J. Schaefer and H. D. Köster
ICP-MS/MS as a tool to diagnose cobalt and chromium intoxications caused by metal hip arthroplasties.
Winter Conference on Plasma Spectrochemistry, Münster (2015) -
Zurek G, Kirchherr H, von Ahsen N, Kühn-Velten WN
Insights into a TDM laboratory: daily routine or adventure?
Pharmacopsychiatry (2014) 47 - A5_1 -
Hiemke C, Baumann P, Bergemann N, Conca A, Dietmaier O, Egberts K, Fric M, Gerlach M, Greiner C, Gründer G, Haen E, Havemann-Reinecke U, Jaquenoud Sirot E, Kirchherr H, Laux G, Lutz UC, Messer T, Müller MJ, Pfuhlmann B, Rambeck B, Riederer P, Schoppek B, Stingl J, Uhr M, Ulrich S, Waschgler R, Zernig G.
AGNP consensus guidelines for therapeutic drug monitoring in psychiatry: update 2011
Pharmacopsychiatry (2011) 44(6):195-235